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COX, Cyclooxygenase

Biochim Biophys Acta Mol Basis Dis 1822:625630

Any factor that affects this intraocular environment, such as aging, genetics, metabolic abnormalities, trauma, radiation, poisoning, local nutritional disorders, and certain systemic metabolic or immune diseases, can directly or indirectly cause the lens to become opaque

Journal of Mass Spectrometry , in press Choi DW, Bandow NL, McEllistrem MT, Semrau JD, Antholine WE, Hartsel SC et al (2010) Spectral and thermodynamic properties of methanobactin from -proteobacterial methane oxidizing bacteria: a case for copper competition on a molecular level

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Also, although lipid-soluble drugs may get into the brain endothelial cell membrane, they may get thrown out just as quickly by efflux transporters