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Therefore, the choice of clinical treatment needs to be weighed against a variety of factors, including efficacy, safety, and individual patient differences, to develop a better treatment plan for subsequent diagnosis and treatment

Whilst adequate levels of all of the B vitamins should be obtainable from a healthy diet, evidence suggests that large sub-sections of the populations of developed countries are suffering deficiencies or marginal deficiencies in one or more B vitamins that will predispose them to a number of negative health consequences, including less than optimal brain function

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The review included studies if they featured patients with AD or mild cognitive impairment (MCI), with available serum levels of Se or Se included with other nutrients