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The accumulation of fat can lead to a dysfunction in the biosynthesis of L-carnitine (Figure 1) in the liver thus inducing a negative feedback loop, whereby less L-carnitine is produced which leads to enhanced impairment of fatty acid oxidation re-enforcing fatty liver disease

When combined with L-Carnitine, a nutrient that transports stored fat into cells to be burned for energy, patients gain both appetite control and enhanced metabolic support

[Epub ahead of print]

doi: 10.1007/s12035-022-02990-5

The distribution of vitamin BT (carnitine) throughout the animal kingdom

American Journal of Medical Genetics Part C: Seminars in Medical Genetics