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doi: 10.1016/j.foodres.2020.109302 166 HossainMNSarkerURaihanMSAl-HuqailAASiddiquiMHObaS

B.DurisK.LekicT.CampbellA.TangJ.et al (2012)

Binding of TCR and coreceptor (CD4 or CD8) to cognate peptide and MHC (signal 1) and costimulation (signal 2) trigger a multitude of (primarily phosphorylation) signaling cascades, including the PI3K-AKT pathway

Current treatment strategies include surgical resection, thyroid hormone replacement therapy, and adjuvant radioactive iodine therapy, achieving a favorable prognosis for PTC, with a 10-year survival rate exceeding 90% [4]

They work by blocking VGCC alpha-2-delta subunits

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