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The speed of onset is generally more rapid compared with the oral route, and for some drugs approaches that for the intravenous route

Posa A, Sel S, Dietz R, Sander R, Paulsen F, Bruer L

By the 1990s, low-dose naltrexone (LDN) was being used in cancer patients and in patients with autoimmune diseases for its observed positive effects on the immune system

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