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Although the exact mechanism is unknown, vitamin B 12 replacement even after a prolonged period (at least up to 2 years) has shown good outcomes in patients with psychosis.56 Therapeutic management In general, vitamin B 12 replacement therapy helps to reverse the haematological abnormalities and psychiatric disorders

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Caspase-3 activity assay 4T1 cells were seeded in 6-well plates at a density of 2 10 5 cells per well and incubated overnight
