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this is due to the increase in size of the boron atoms atomic radius compared to carbon, as well as the fact that boron has a weaker bond strength than carbon

Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy

& Kollman, P

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Moreover, full-length BPC157 or single-site alanine-mutated BPC157 was dissolved in HBS-EP Buffer (Cytiva) at concentrations ranging from 1.89 nM to 31.25 nM through serial 2-fold dilutions