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Increased levels of eosinophil peroxidase (EPO) and myeloperoxidase (MPO) parallel the numbers of eosinophils and neutrophils, respectively, and are found at higher than normal levels in peripheral blood, induced sputum and BAL fluid 36 of patients with asthma

At the same time, iron overload may promote oxidative stress, neuroinflammation, ferroptosis, and neuronal injury, potentially exacerbating ASD-associated symptoms and comorbidities

In a separate experiment, 60 male Balb/c mice (6 weeks old) were intraperitoneally infected with 200 L of bacterial suspension (1 10 9 CFU/mL) and randomly divided into four groups

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Koite and colleagues [475] found that supplementation with 2 g/L of Arthrospira extract (containing 1 g/L of phycocyanin and 0.5 g/L of Spirulysat, which includes proteins, amino acids, enzymes, vitamins, and minerals) for 12 weeks led to a reduction in urinary isoprostane levels

In transfusion medicine, these discoveries contribute to advancements in storage methodologies, including metabolic rejuvenation and focused modulation of membrane pathways to mitigate storage lesions and enhance post-transfusion effectiveness (80)