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[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Strong AP, Haeusler S, Weatherall M, Krebs J

& Alm, E

A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range

While injections are a common method of administering Vitamin B12, there are alternative options available, such as oral supplements and nasal sprays

In the key Phase 3 ATTAIN-1 trial published in the New England Journal of Medicine in 2025, once-daily orforglipron 36 mg produced mean body weight reductions of 11.2% at 72 weeks in adults with obesity, with nearly 55% of participants achieving at least 10% weight loss and 36% achieving 15% or more

An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1)
