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Lastly, most trials (and observational studies) did not consider duration of diabetes as an eligibility criterion or account for this by subgroup analyses

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It was found that probiotics VSL#3 treatment could upregulate the expression of microRNA-146a (miR-146a) and block the BTG2/Bax (B-cell translocation gene 2/Bcl-2-associated X protein) axis in POCD mice, thus inhibiting neuronal apoptosis and reducing oxidative stress (Mao et al., 2021)

The answer is not straightforward

Silvestro S., Raffaele I., Quartarone A., and Mazzon E., Innovative Insights Into Traumatic Brain Injuries: Biomarkers and New Pharmacological Targets, International Journal of Molecular Sciences 25, no
