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Skeletal muscle ageing models preclinical investigation has explored NNMT inhibition in models of age-related muscle dysfunction and stem-cell quiescence

In cancer metabolism research, 5-amino-1MQ offers investigators a precise tool for studying the role of NNMT in tumor cell biology and metabolic reprogramming

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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts