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Deficiency can be corrected with vitamin B-12 supplements even if metformin is continued

doi: 10.1146/annurev-nutr-071714-034330 202

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Dosing: 400-800 micrograms per day for heterozygous (CT)

Constitutive and -naphthoflavone-induced expression of -glutamylcysteine synthetase heavy subunit gene is regulated by distal antioxidant response element/TRE sequence
