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doi: 10.1007/s00204-022-03367-2 75 HaiserH
doi: 10.1159/000503835 104
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When 4% of patients treated with pemetrexed-containing chemotherapy would experience G4 neutropenia, the accrual of at least 50 patients was needed, assuming that a significant factor of 20 to 25 would be identified for the outcome in the multivariate logistic regression analysis, in general
Running one without the other means one mechanism is always the bottleneck
Washington, DC: American Psychiatric Association (1980)
