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In LAB, this is a current frontier and one with a lot of possible rewards
NES represents normalized enrichment score
The carboxy group of the substrate also forms hydrogen bonds with the peptide nitrogen of Ser-452 and possibly its side chain hydroxy group
The definition of high-risk populations without obvious characteristics, the uncertainty of the time from precancerous lesions to invasive cancer, metastasis, and recurrence have hindered chemoprevention research
Daruich A, Picard E, Boatright JH, Behar-Cohen F
A second aromatic dyad within AcP10, composed of Y207 and F210, also latches onto eIF2Bs C-terminal helix (Fig
