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For instance, in fumarate hydratase-deficient cancer cells, accumulated fumarate results in the production of succinate GSH, resulting in increased mitochondrial ROS and subsequent HIF-1 activation

Each zone is assigned a score based on the percentage of gray hair, and an overall graying score is assigned based on the cumulative assessment of the five regions

[DOI] [PubMed] [Google Scholar] 22.Swart EC, Serra V, Petroni G, Nowacki M

Attempts to identify regulatory steps in the pathways that could be manipulated to obtain unlimited AsA production were also less successful than expected, confirming the difficulties in unleashing AsA synthesis

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Thereafter, we elaborate on recent research advances on carbon dot-based sensors for the selective and sensitive detection of a wide range of analytes, including heavy metals, cations, anions, biomolecules, biomarkers, nitroaromatic explosives, pollutants, vitamins, and drugs