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A study of the effects of formononetin on fluorescein isothiocyanate-induced AD murine model (10 mg/kg) and the same human keratinocyte cell line (10 M) confirmed reduced TSLP levels and upregulated TNF- induced protein 3 (TNFAIP3/A20) by G protein-coupled estrogen receptor (GPER) activation [124]

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