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These murine models were initially presented with corticosteroids, which reportedly contributed to severe muscular damage in these murine models

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Trammell S

17 GSTs catalyze glutathionylation or S-glutathionylation, a reversible posttranslational modification regulating protein function, which is significantly promoted by reactive nitrogen species and reactive oxygen species (ROS)

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[] Bile acid itself may act as an immunometabolic drug that not only affects cholestasis but also has immunological and inflammatory effects that are associated with cholestasis