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Mapson and Isherwood6 found with the very sensitive fluorometric method the formation of very small amounts of NADPH2 (0.9 103 mol./ml.).

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Commonly found in plant foods, PQQ (pyrroloquinoline quinone), a polyphenol, is essential to energy metabolism in the cells and has strong antioxidant properties

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This Review discusses methionine metabolism in the context of nutrition and the potential of targeting methionine metabolism in cancer through dietary or pharmacological intervention.
