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[DOI] [PMC free article] [PubMed] [Google Scholar] 192.Ringseis R, Wen G, Eder K

Once reconstituted, however, molecular motion increases

Consistent with reports in other cancer types showing that GPX2 overexpression promotes cisplatin resistance by suppressing ROS accumulation, our findings suggest that NAC-associated upregulation of GPX2 may enhance intracellular antioxidant defenses, thereby promoting survival of residual tumor cells and contributing to chemoresistance [21, 22]