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During aging, changes in gene expression have been consistently reported (Rangaraju et al., 2015), and these changes can be deleterious or protective depending on the targeted gene and how its expression is regulated

I also gave up my usual evening actives (AHA, BHA, vitamin C and retinol, one per night) while using these products, as I didnt want the results to be influenced by any interactions between the ingredients while on my skin

10.1165/rcmb.2012-0473OC 46 De StefanoD.UngaroF.GiovinoC.PolimenoA.QuagliaF.CarnuccioR

The compound has been shown in cell-based research to upregulate VEGFR2 transcript levels, increase phosphorylation of downstream signalling intermediates after VEGF stimulation, and enhance endothelial tube formation in matrigel assays

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