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doi: 10.12659/AJCR.921431 70
If serum B12 is over 900 pg/mL with no clinical reason to be that high and youre not treating a documented deficiency, yes, tapering down makes sense

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Control shRNA without carrying any gene was also transfected into DPCs

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Their strategic positioning between blood vessels and synapses allows them to regulate neurovascular coupling and support neuronal acticity 14
