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The absence of mucin, a highly glycosylated polymeric protein in the mucous layer, makes an animal vulnerable to intestinal inflammation, which leads to the development of spontaneous colitis and confers a predisposition to the development of colorectal cancers (Fig

doi: 10.1006/neur.1995.0016

Thus, we revealed an antecedent early disturbance decisive for further isoprenaline myocardial lesion progression

Two main polarisations of TAMs include M1-like macrophages, which exhibit anti-tumour activities by stimulating the adaptive immune response and inflammation and, conversely, M2-like macrophages, which exhibit tumour promoting activities by suppressing the immune response in the TME [183]