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All these results allowed to conclude that APR-246 induces early cell death by ferroptosis, a recently described non-apoptotic form of regulated cell death that links together membrane lipid peroxidation, cysteine and iron metabolism, glutathione peroxidase activity and oxidative stress (as summarized in Figure 4A 2325 )

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Borrelia burgdorferi is dependent upon the mammalian or tick host for the provision of amino acids and other required components

16 Additional therapy for young children with spastic cerebral palsy: a randomised controlled trial

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