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The results indicated that the group receiving treatment with FEE 80 mg/kg was able to significantly alleviate the principal symptoms of CFA-induced RA

Oxidative stress primarily refers to the process of oxidative damage resulting from an imbalance between oxidative and antioxidant systems in cells and tissues, leading to the accumulation of free radicals and ROS (41)

(1986) Oxygen uptake and glutamate dehydro-genase release in isolated renal tubules from rat kidney

However, it should not be ruled out that problems may already exist above this level