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These LL-37/DNA complexes are potent activators of plasmacytoid dendritic cells, triggering massive production of type I interferons, the same cytokines that drive the "interferon signature" characteristic of active lupus

TB-500 (synthetic thymosin -4 fragment, LKKTETQ, 889 Da) shares tissue-healing indications but acts through a different mechanism (G-actin sequestration, Ac-SDKP anti-fibrosis)

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Bray, G

These symptoms typically appear in the hand, but they can also affect the arm and wrist