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The crude extracts also induced analgesia, albeit at a slightly lower % MPE (Day 4 for crude 20 mg/kg with highest %MPE at 43 6% and Day 1 for crude 10 mg/kg with highest %MPE at 45 3%) compared to the morphine group

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The term ROS encompasses a diverse array of oxidant molecules with varying properties and biological functions, ranging from cell signaling to causing cellular damage, as observed in the case of free radicals 44

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Furthermore, localized release of NT-3 has been explored in animal models, and the results demonstrated effective neuroregeneration [470, 471] and synaptic restoration [113, 472]

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