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The use of AOX could also prevent direct photooxidation of existing melanin in superficial skin cells [25, 59,60,61]

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In addition, a newer class of drugs called sodium-glucose cotransporter-2 (SGLT2) inhibitors demonstrated cardioprotective properties in trials with individuals who have diabetes and CKD, as well as people with CKD who do not have diabetes

(58) *A note about NAC: Per a July 2020 warning letter from the FDA, there is currently some debate on whether or not NAC can be sold as a supplement, because it was approved for use as a drug in 1963

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The other major determinant of spine distribution and dynamics lies at the presynaptic side: the identity and geometry of presynaptic axons and the availability of axonal boutons