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Gynecomastia resolved either completely or partially in 80% of subjects after finasteride was discontinued, however, in at least 2 cases, a new primary malignancy of primary intraductal breast cancer subsequently developed

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Of the 170 RpoS-regulated genes identified in DMCs, all but 3 ( bb0228 , bb0454 , and bbb29/malX-2 ) were restored to near-WT levels by trans -complementation with rpoS expressed under its native promoter (Supplemental Table 3)