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In the final message from the client, it sets the 'status indicator' bit from 0 to 1 to communicate that no further segments will be sent

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Bioconjugate Chemistry 2026 , 37 (1) , 169-179

The catalytic cycle of Grx2 is also quite similar to Grx1 except that the Grx2SSG intermediate can be reduced by NADPH and TrxRD
