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Acknowledgements The authors wish to thank the Department of Biology and the Research Council of Islamic Azad University, Rasht Branch, for providing laboratory support and scientific guidance throughout the study

HSPs play a substantive role in PD pathology, with several HSPs shown to co-localize with Syn in LBs 27,94

Ferroptosis inhibitors are sometimes used to assess the role of ferroptosis in the pathophysiology

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For AD status, we downloaded GWAS summary statistics data from the European Alzheimer & Dementia Biobank (EADB) consortium 43

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