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Anaphylactic shock is the most serious adverse effect

For people following a plant-based diet that choose to exclude animal products, it can be difficult to get enough B12

A 2025 narrative review of musculoskeletal research described both the regenerative findings and the open questions about translation to human clinical use (PMID 40789979)

These provide antioxidants to help slow bacteria growth and sulfur compounds that reduce odor

[1] The American Diabetes Association (ADA) primarily recommends B12 monitoring for patients on long-term metformin therapy rather than for those on GLP-1/GIP receptor agonists

You might feel sharp, electric-like sensations, burning pain, or numbness that worsens when you sneeze, cough, or sit for long periods