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The specific mechanism of potential side effects when T1 is combined with targeted therapy drugs and immunotherapy drugs, as well as the investigation of whether T1 has other side effects, are also worthwhile research areas because prior basic research has only combined chemotherapy drugs

Tubastatin A Potently Inhibits GPX4 Activity to Potentiate Cancer Radiotherapy Through Boosting Ferroptosis

Stolte, M., G
GPCRs are critical regulators of cellular function and play a fundamental role in maintaining physiologic homeostasis (Weis and Kobilka, 2018)

They were mainly gastrointestinal, and only one patient in that group discontinued due to side effects

doi: 10.1007/s00213-006-0635-5 238 MerchnANavarroSVKleinABAznarSCampaLSuolCet al
