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Adderall carries high addiction potential because it produces dopamine surges of 200 to 300% above baseline through DAT blockade

Though liver is the primary site where CYP2E1-mediated metabolism exerts its most damaging effect, extra-hepatic tissues are often affected to a various degree as well 44,45

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at 3.33 mg/mL, 1 unit = 0.01 mL 33.3 mcg

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This therapeutic pipeline includes: (1) identification of target genes (e.g., high-risk HLA alleles, PTPN22, INS)