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The decline in LVDP was attenuated with 4-ClDzp, with 4-ClDzp treated hearts having significantly higher LVDP from 22 minutes after diamide through the duration of the protocol (Figure 4)

Considering that GSH has a very short half-life [228], gene transfer of glutathione synthesis components such as GCLC, GCLM, and GS could be a useful therapeutic approach in I/R injury through an increase in GSH intracellular concentration [215,216]

(2007) showed for the first time in an in vivo model that high hepatic GSH (1.5-fold), cysteine (15-fold), and glutamate cysteine ligase activity (1.5-fold) levels correlate with increased telomerase activity

Advancing shellfish immunotherapy will require the integration of precision diagnostics, targeted interventions, and robust clinical validation to ensure safe, effective, and individualized care