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Considering that LEC-autophagy provides the fuel supply to maintain FAO and ultimately lymphatic proliferation and migration, it is tempting to speculate that dietary or life-style conditions that stimulate autophagy (e.g., caloric restriction, keto-diet, improved exercise) may facilitate restoring lymphatic functions in pathological conditions such as obesity or lymphedema

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Thereby, it protects or decreases neuronal cells from A-induced apoptosis and cisplatin-induced neuronal injury in a dose-dependent manner (Jang et al., 2004

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Salomidi, M., Katsanevakis, S., Issaris, Y., Tsiamis, K
Plant Cell Environ 34(2011):2132 Rawlins MR, Leaver CJ, May MJ (1995) Characterisation of an Arabidopsis thaliana cDNA encoding glutathione synthetase