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A recent study reported that IECs in Crohn's disease indeed exhibit impaired GPX4 activity and an increase of 4-hydroxy-2-nonenal (4-HNE) immunoreactivity, indicating a vulnerability of IECs to ferroptosis in Crohn's disease [352], although the therapeutic potential of targeting ferroptosis for Crohn's disease remains elusive
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The most commonly reported side effects are gastrointestinal in naturenausea, vomiting, or diarrhoeaparticularly when starting oral supplementation

Mitochondrial impairment also occupies a central role in PD

2.7 Flow cytometry At 56 and 84 days respectively, the rats were excessively anesthetized and sacrificed

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