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Importantly, MSC-EVs possess the unique ability to cross biological barriers, such as the blood-brain barrier, broadening their therapeutic potential

(2) publication types including original research articles, systematic reviews, meta-analyses, and clinical trials

Any injection-related adverse effects typically subside within one to three days following administration

Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]

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