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doi: 10.1001/jama.2011.1437

Science 375 , 296301 (2022)

Additionally, corticosteroids (prednisone and betamethasone) and NSAIDs (ibuprofen) reduced the expression of IL-6 and IL-8, inactivated STAT3 and NF-B signaling pathways, and reduced the expression of collagen I, MMP-1 and MMP-13, which protect against OA

This tricks the brain into perceiving low estrogen, triggering increased LH and FSH release

Stack carefully avoid overwhelming the body with too many overlapping compounds at once
