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We found that MPTP animals had significantly lower ratios of SHexCer(t/d42:2), SHexCer(t/d43:2) and SHexCer(t/d40:1) in GPi compared to controls, with similar depletion observed in LID animals compared to non-LID animals (Fig

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For instance, Mg reduces Cd accumulation by decreasing nitrate reductase-mediated NO production in Panax notoginseng roots ( Based on these findings, Mg alleviates metal toxicity through two primary pathways: (i) physicochemical interactions at the root surface involving the cell wall and plasma membrane, and (ii) intracellular physiological protection mediated by Mg 2+

doi:10.1186/s12905-020-00930-w

However, OXPHOS is not a perfect mechanism