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Ensure the area is clean and sanitized before injecting

The trafficking of BDNF through the RSP is proposed to be essential for its function, as the dysregulation of BDNF trafficking has been implicated in numerous neuronal disorders, as disruptions in sorting receptors, motor protein complexes, or scaffold proteins can impair BDNF targeting to the RSP and reduce activity-dependent secretion [3, 4, 11,12,13,14,15,16,17,18,19,20,21,22]

Extracellular matrix remodelling as a potential therapeutic target

Such claims should be read as unproven

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Elevated cortisol observed relative to placebo in the 2008 randomized controlled trial
