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This simultaneous engagement of peripheral pigmentary and central behavioural melanocortin receptor biology in a single compound makes MT-II uniquely valuable for research examining the mechanistic relationships between melanocortin receptor subtypes and the distinct biological systems they govern

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Furthermore, as well as being an effective alcoholism treatment, these findings suggest that MT-2 taps into a fundamental process of cravings and desire in mammals

10.1186/s12864-020-06944-w Summary Keywords TMAO (trimethylamine oxide), MAFLD (metabolic associated fatty liver disease), trimethylamine, TMA precursor, FMO3, unfolded protein response, oxidative stress Citation Li X, Hong J, Wang Y, Pei M, Wang L and Gong Z (2021) Trimethylamine-N-Oxide Pathway: A Potential Target for the Treatment of MAFLD

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