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For trial details see the Motus study

Yes, and in fact, some research designs do exactly that to separate endocrine-mediated effects from direct fat cell effects in the same experimental system

Am J Health Syst Pharm 62(14):14941497 Garbino J, Henry JA, Mentha G, Romand JA (2001) Ecstasy ingestion and fulminant hepatic failure: liver transplantation to be considered as a last therapeutic option

Int J Mol Sci 24(9):8323 Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R (1999) Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

Plant-based diets have been suspected of producing lower bone mineral density, especially in young, growing adults

Linear-peptide screens in the 1990s found the FYXWF pattern