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Description
Nat Commun 13 , 5184 (2022)

Filipovic, M
Because NAC works by gradually supporting glutathione levels and internal processes, regular daily use is usually recommended for best results

For the experiment, 56 healthy male adult rats were randomly selected and were divided into seven equal groups (n = 8) and treated as: NC as normal control group (normal saline 10 ml/kg body weight/day, orally), high lipid diet group (HLD, 10 ml/kg body weight/day, orally which equates to 600 ml/60 kg of humans respectively), monosodium glutamate group (MSG, 600 mg/kg body weight/day, orally which equates to 3.6 g/60 kg of humans respectively), HLD + MSG group (HM, 10 ml/kg body weight/day, orally + 600 mg/kg body weight/day, orally), HM + low dose of EECGL (EECGLL, 200 mg/kg body weight/day, orally which equates to 1.2 g/60 kg of humans respectively), HM + medium dose of EECGL (EECGLM, 400 mg/kg body weight/day, orally which equates to 2.4 g/60 kg of humans respectively), HM + high dose of EECGL (EECGLH, 600 mg/kg body weight/day, orally which equates to 3.6 g/60 kg of humans respectively)
These two ingredients help improve stability and protective effects
Cells were collected at two time intervals (1 h and 2 h) and treated as described above
