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The detrimental impacts of heavy metals on human health are largely linked to their capacity to interfere with antioxidant defense mechanisms, primarily through their interaction with intracellular glutathione (GSH) or sulfhydryl groups (R-SH) of antioxidant enzymes such as superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), glutathione reductase (GR), and other enzyme systems
Klyosov, A
& Papagiannakopoulos, T
19 Reductive synthesis NADPH is also a crucial electron source for several reductive synthesis reactions, including fatty acids, amino acids, nucleotides, and steroids synthesis to sustain rapid tumor cell growth
10.1016/j.neulet.2008.06.001 Neurosci
