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Description
Biochemical Pharmacology, 147, 141152

Long-term studies in animals to evaluate carcinogenic potential have not been done

This reaction simultaneously depletes two critically important metabolic cofactors: SAM (the universal methyl donor for hundreds of epigenetic and biosynthetic reactions) and nicotinamide (the precursor for NAD+ biosynthesis via the salvage pathway)

25 (8), e515e529

A gentle preservative

Doses of folic acid greater than 0.1 mg per day may result in hematologic remission in patients with vitamin B12 deficiency
