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BMJ (Clinical research ed.)

2014 Oct 1;62(39):9499-506

Under oxidative stress, thiol groups of cysteine residues are oxidized to form reversible intramolecular disulfide bonds (SS) and cysteine sulfenic acids (CysSOH) or irreversible products such as sulfinic acids (CysSO 2 H) and sulfonic acids (CysSO 3 H) (Kanemura et al

CZ: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Visualization, Writing original draft, Writing review & editing

The hydroxyl radical reacts promptly with any biological molecule like lipid, protein and DNA and cause severe consequence in the pathogenesis of SLE

10.1016/j.jep.2014.11.012 111 WangY.HuangM.LuX.WeiR.XuJ