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10.3389/fimmu201901462 45
The research is clear, the mechanisms are understood, and the tools are available
Peng DH , Tedeschi A, Herdeis L, Schaaf O, Savarese F, Rocchetti F, Popow J, Huber HJ, Wilding B, Treu M, Fuchs J, Breker J, Wunberg T, Schischlik F, Lipp J, Williams M, Chandler V, Deckard CE, Ramamoorthy V, Daniele JR, Kopetz S , Kim M, Gibbons DL, Vellano CP, Marszalek JR, Heffernan TP, McConnell D, Pearson M, Kraut N, Rudolph D
This lysosomal insufficiency impaired autophagy and contributed to AP pathogenesis
In parallel, Ca 2+ dysregulation, endoplasmic reticulum stress and mitochondrial dysfunction further exacerbate astrocytic impairment 114
A., Mooers, B
