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Despite advances in knowledge about the pathogenesis of neurodegenerative disorders, effective treatments to combat neurodegenerative disorders caused by MetS have not been developed to date

PLoS ONE 14(4): e0215815

As the negative control, MLB was added to the medium without cells

doi: 10.1016/j.ygeno.2021.01.022 70 ShuK.LiuX
481 This Fe-MOF-based system, loaded with MG132, inhibited proteasome activity and NF-B p65 phosphorylation, leading to the accumulation of proapoptotic proteins and the disruption of tumor homeostasis

To counteract ERS, cells initiate the UPR via three major pathwaysPERK, inositol-requiring enzyme 1 (IRE1), and activating transcription factor 6 (ATF6)to coordinate adaptive repair and death decisions [206]
