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(2013) Role of Glutathione in Cancer Progression and Chemoresistance
These findings have stimulated clinical development attempts, particularly for NAD + modulators deemed suitable for human trials in terms of safety and upscaling, such as natural precursors
The GPX family encompasses eight members, designated as GPX1-8, which collectively contribute to inhibiting oxidative stress and maintaining redox equilibrium [46]
For example, C-Myc amplified in ovarian cancer cells inhibits ferroptosis by inducing NCOA4-mediated ferritinophagy [94] , but erastin selectively kills iron-addicted ovarian cancer cells by inducing ferroptosis and promoting NCOA4-mediated ferritinophagy and mitochondrial dysfunction [95]
Thus, results of intervention trials of B vitamin supplementation are conflicting
Baca Juga: Mitos atau fakta
