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For example, rats do not have a gall bladder an important component of the hepatobiliary system

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It acts as a potent antioxidant that binds to toxins, heavy metals, and harmful chemicals alike, facilitating their elimination from the body
Tumor-targeted cascade nanoreactor based on metal-organic frameworks for synergistic ferroptosis-starvation anticancer therapy

Over time, these crystals can aggregate and form stones (Jones, Ghassemzadeh 2018
